Lemtrada

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:drug
gptkbp:administeredBy intravenous infusion
gptkbp:approvedBy gptkb:FDA
gptkb:EMA
2014
gptkbp:ATCCode L04AA34
gptkbp:brand alemtuzumab
gptkbp:CASNumber 216503-57-0
gptkbp:chemicalFormula C6428H9956N1714O2016S40
gptkbp:contraindication HIV infection
active infection
gptkbp:cost high
gptkbp:halfLife 2 weeks
https://www.w3.org/2000/01/rdf-schema#label Lemtrada
gptkbp:indication relapsing forms of multiple sclerosis
gptkbp:legalStatus prescription only
gptkbp:manufacturer gptkb:Sanofi_Genzyme
gptkbp:mechanismOfAction gptkb:monoclonal_antibody
gptkbp:pregnancyCategory C
gptkbp:pregnancyWarning may cause fetal harm
gptkbp:prescriptionStatus Rx only
gptkbp:riskEvaluationMitigationStrategy required in US
gptkbp:routeOfAdministration intravenous
gptkbp:sideEffect autoimmune disorders
thyroid disorders
infections
infusion reactions
gptkbp:storage 2-8°C
gptkbp:target CD52
gptkbp:UNII J39AR2B3D0
gptkbp:usedFor multiple sclerosis
gptkbp:bfsParent gptkb:赛诺菲
gptkbp:bfsLayer 6