Statements (58)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:physicist
|
| gptkbp:bfsLayer |
5
|
| gptkbp:bfsParent |
gptkb:lung_adenocarcinoma
gptkb:biliary_tract_cancer |
| gptkbp:affects |
MAPK signaling pathway
P I3 K signaling pathway |
| gptkbp:are |
a subject of ongoing research
a subject of genetic counseling common in cancer patients a biomarker for therapy selection a critical component of cancer biology a focus of drug development a focus of molecular diagnostics a key factor in cancer research a key player in oncogenesis a major focus of translational research a significant area of study in oncology a target for immunotherapy a target for novel drug development important in personalized medicine not present in all cancers often studied in research |
| gptkbp:associated_with |
gptkb:healthcare_organization
metastasis |
| gptkbp:can_be |
inherited
linked to environmental factors studied in animal models detected in blood tests studied for resistance mechanisms analyzed by sequencing analyzed for therapeutic implications analyzed in liquid biopsies associated with lifestyle factors associated with patient outcomes associated with specific clinical features associated with specific mutations linked to specific ethnic groups monitored for treatment response targeted by combination therapies targeted for therapy |
| gptkbp:can_lead_to |
tumorigenesis
uncontrolled cell growth |
| gptkbp:exhibits |
heterogeneity
|
| https://www.w3.org/2000/01/rdf-schema#label |
KRAS mutations
|
| gptkbp:impact |
cell signaling pathways
|
| gptkbp:influence |
tumor microenvironment
|
| gptkbp:is_aimed_at |
specific therapies
|
| gptkbp:is_found_in |
gptkb:healthcare_organization
|
| gptkbp:is_involved_in |
GT Pase activity
nucleotide substitution |
| gptkbp:is_linked_to |
treatment resistance
|
| gptkbp:is_often_depicted_as |
adenocarcinomas
|
| gptkbp:is_often_used_in |
smokers
|
| gptkbp:is_recognized_by |
tumor samples
|
| gptkbp:is_studied_in |
clinical trials
|
| gptkbp:recognizes |
biopsy
|
| gptkbp:resulted_in |
poor prognosis
|
| gptkbp:scientific_classification |
driver mutations
|