gptkbp:instance_of
|
gptkb:pharmaceuticals
|
gptkbp:application
|
applied directly to the affected toenail
|
gptkbp:approves
|
gptkb:FDA
|
gptkbp:available_in
|
gptkb:various_countries
|
gptkbp:brand
|
gptkb:Jublia
|
gptkbp:class
|
antifungal
|
gptkbp:clinical_trial
|
Phase III
demonstrated efficacy in treating onychomycosis
|
gptkbp:clinical_use
|
applied once daily
|
gptkbp:condition
|
onychomycosis
|
gptkbp:contraindication
|
hypersensitivity to efinaconazole
|
gptkbp:dosage_form
|
gptkb:liquid
|
gptkbp:drug_interactions
|
none significant reported
|
gptkbp:duration
|
24 hours
48 weeks
|
gptkbp:form
|
topical solution
|
gptkbp:healthcare
|
2014-07-24
|
https://www.w3.org/2000/01/rdf-schema#label
|
Jublia
|
gptkbp:ingredients
|
gptkb:efinaconazole
|
gptkbp:invention
|
patented
|
gptkbp:is_effective_against
|
shown in clinical trials
|
gptkbp:label
|
includes instructions for use
|
gptkbp:manufacturer
|
gptkb:Valeant_Pharmaceuticals
|
gptkbp:marketed_as
|
gptkb:2014
|
gptkbp:mechanism_of_action
|
inhibits fungal cell membrane synthesis
|
gptkbp:packaging
|
bottle with applicator
|
gptkbp:patient_education
|
important for understanding treatment
|
gptkbp:patient_population
|
adults
|
gptkbp:pharmacokinetics
|
minimal systemic absorption
|
gptkbp:pharmacy_availability
|
widely available
|
gptkbp:previous_name
|
no
|
gptkbp:price
|
varies by pharmacy
|
gptkbp:provides_guidance_on
|
recommended for mild to moderate cases
|
gptkbp:requires
|
gptkb:true
available online
|
gptkbp:research
|
showed improvement in nail appearance
|
gptkbp:safety_features
|
generally well tolerated
|
gptkbp:safety_measures
|
for external use only
|
gptkbp:service_frequency
|
once daily
|
gptkbp:side_effect
|
allergic reaction
skin irritation
redness
stinging
burning sensation
|
gptkbp:storage
|
room temperature
|
gptkbp:treatment
|
around 50%
improved nail health
topical antifungal therapy
|
gptkbp:treatment_limitations
|
not for use in children
|
gptkbp:type_of_care
|
important for treatment success
|
gptkbp:used_for
|
treating toenail fungus
|
gptkbp:bfsParent
|
gptkb:Valeant_Pharmaceuticals
|
gptkbp:bfsLayer
|
6
|