Statements (25)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:drug
|
gptkbp:approvalYear |
2006
|
gptkbp:ATCCode |
A10BH01
|
gptkbp:CASNumber |
gptkb:486460-32-6
|
gptkbp:chemicalFormula |
C16H15F6N5O
|
gptkbp:contraindication |
gptkb:diabetic_ketoacidosis
type 1 diabetes |
gptkbp:drugClass |
DPP-4 inhibitor
|
gptkbp:eliminationHalfLife |
12.4 hours
|
gptkbp:form |
gptkb:tablet
|
gptkbp:genericName |
gptkb:sitagliptin
|
https://www.w3.org/2000/01/rdf-schema#label |
Januvia
|
gptkbp:legalStatus |
prescription only
|
gptkbp:manufacturer |
gptkb:Merck_&_Co.
|
gptkbp:mechanismOfAction |
inhibits dipeptidyl peptidase-4
|
gptkbp:pregnancyCategory |
Category B (US)
|
gptkbp:proteinBinding |
38%
|
gptkbp:routeOfAdministration |
oral
|
gptkbp:sideEffect |
headache
upper respiratory tract infection nasopharyngitis hypoglycemia (when combined with other drugs) |
gptkbp:usedFor |
gptkb:type_2_diabetes_mellitus
|
gptkbp:bfsParent |
gptkb:Merck_&_Co.
|
gptkbp:bfsLayer |
4
|