|
gptkbp:instanceOf
|
gptkb:drug
hormone
|
|
gptkbp:administrationTiming
|
30 minutes before meals
|
|
gptkbp:appearance
|
clear solution
|
|
gptkbp:ATCCode
|
A10AB01
|
|
gptkbp:brand
|
gptkb:Actrapid
gptkb:Humulin_R
gptkb:Novolin_R
|
|
gptkbp:CASNumber
|
11061-68-0
|
|
gptkbp:contraindication
|
hypersensitivity to insulin
|
|
gptkbp:discoveredBy
|
gptkb:Frederick_Banting
gptkb:Charles_Best
|
|
gptkbp:discoveredIn
|
1921
|
|
gptkbp:duration
|
6 to 8 hours
|
|
gptkbp:eliminationHalfLife
|
4 to 6 minutes
|
|
gptkbp:hasMolecularFormula
|
C257H383N65O77S6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Insulin regular
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
binds to insulin receptor
|
|
gptkbp:MedlinePlusID
|
a601165
a682399
|
|
gptkbp:metabolism
|
gptkb:kidney
liver
|
|
gptkbp:onset
|
30 minutes
|
|
gptkbp:origin
|
human insulin
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:prescribes
|
gptkb:gestational_diabetes
gptkb:type_2_diabetes
gptkb:diabetic_ketoacidosis
type 1 diabetes
hyperkalemia
|
|
gptkbp:prescriptionRequired
|
yes
|
|
gptkbp:producedBy
|
recombinant DNA technology
|
|
gptkbp:product
|
polypeptide
|
|
gptkbp:PubChem_CID
|
16129678
DB00030
|
|
gptkbp:routeOfAdministration
|
subcutaneous injection
intravenous injection
|
|
gptkbp:RxNormID
|
7052
|
|
gptkbp:sideEffect
|
gptkb:hypoglycemia
injection site reaction
weight gain
|
|
gptkbp:storage
|
refrigerate
|
|
gptkbp:UNII
|
1F7A44V6OU
|
|
gptkbp:usedFor
|
gptkb:diabetes_mellitus
|
|
gptkbp:Vaccine
|
no
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
included
|
|
gptkbp:bfsParent
|
gptkb:insulin
|
|
gptkbp:bfsLayer
|
6
|