Imerslund-Gräsbeck syndrome

GPTKB entity

Statements (27)
Predicate Object
gptkbp:instanceOf gptkb:genetic_disorder
gptkb:rare_disease
gptkbp:affects children
gptkbp:alsoKnownAs Megaloblastic anemia 1
Megaloblastic anemia due to selective vitamin B12 malabsorption
gptkbp:category gptkb:hematologic_disease
gptkb:inherited_metabolic_disorder
gptkbp:complication developmental delay
neurological impairment
gptkbp:diagnosedBy low vitamin B12 levels
urinary protein excretion
gptkbp:firstDescribed 1960
Olaf Imerslund
Ralph Gräsbeck
gptkbp:inheritance autosomal recessive
gptkbp:mutationAssociatedWith AMN gene
CUBN gene
gptkbp:OMIM 261100
gptkbp:prevalence very rare
gptkbp:symptom proteinuria
failure to thrive
neurological symptoms
megaloblastic anemia
gptkbp:treatment vitamin B12 injections
gptkbp:bfsParent gptkb:Amn
gptkbp:bfsLayer 7
https://www.w3.org/2000/01/rdf-schema#label Imerslund-Gräsbeck syndrome

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