Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
immunoglobulin G subclass
|
| gptkbp:activatesComplement |
strongly
|
| gptkbp:bindsFcGammaReceptors |
yes
|
| gptkbp:canCrossPlacenta |
yes
|
| gptkbp:discoveredBy |
human immunology researchers
|
| gptkbp:encodedBy |
IGHG3 gene
|
| gptkbp:firstIgGSubclassProduced |
yes
|
| gptkbp:foundIn |
gptkb:human
|
| gptkbp:halfLife |
7 days
|
| gptkbp:hasHeavyChain |
gamma-3 chain
|
| gptkbp:hasLongestHingeRegion |
true
|
| https://www.w3.org/2000/01/rdf-schema#label |
IgG3 subclass (human)
|
| gptkbp:isotypeOf |
IgG (human)
|
| gptkbp:percentageOfTotalIgG |
8%
|
| gptkbp:roleInImmunity |
antibody-dependent cellular cytotoxicity
opsonization neutralization of pathogens |
| gptkbp:serumConcentration |
0.4–1.0 mg/mL
|
| gptkbp:structure |
high flexibility
long hinge region many inter-heavy chain disulfide bonds |
| gptkbp:bfsParent |
gptkb:Protein_A
|
| gptkbp:bfsLayer |
7
|