Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
cytokine
|
| gptkbp:discoveredBy |
2000
|
| gptkbp:encodedBy |
IL21 gene
|
| gptkbp:fullName |
Interleukin 21
|
| gptkbp:function |
regulates immune response
enhances cytotoxicity of NK cells stimulates proliferation of B cells stimulates proliferation of T cells |
| gptkbp:gene |
IL21
|
| gptkbp:HGNC_ID |
HGNC:6000
|
| https://www.w3.org/2000/01/rdf-schema#label |
IL 21
|
| gptkbp:involvedIn |
immunotherapy
autoimmune diseases allergic responses |
| gptkbp:locatedOnChromosome |
gptkb:4q27
|
| gptkbp:modulatedBy |
inflammatory response
antibody production |
| gptkbp:OMIM |
605384
|
| gptkbp:producedBy |
activated CD4+ T cells
natural killer T cells |
| gptkbp:recipient |
IL-21 receptor
|
| gptkbp:regulates |
Th17 cell development
differentiation of T cells immunoglobulin production differentiation of B cells differentiation of NK cells follicular helper T cell development |
| gptkbp:relatedTo |
IL-2 family
|
| gptkbp:structure |
four-helix bundle
|
| gptkbp:target |
therapeutic antibodies
|
| gptkbp:UniProtID |
gptkb:Q9H9Q4
|
| gptkbp:bfsParent |
gptkb:Illinois_Route_21
gptkb:Illinois_Route_60 |
| gptkbp:bfsLayer |
7
|