Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
cardiomyopathy |
| gptkbp:affects |
heart muscle
|
| gptkbp:associatedWith |
sudden death in young athletes
|
| gptkbp:canBeAsymptomatic |
true
|
| gptkbp:cause |
gptkb:arrhythmia
heart failure shortness of breath chest pain sudden cardiac death syncope |
| gptkbp:causedBy |
mutations in sarcomere protein genes
|
| gptkbp:characterizedBy |
thickening of the heart muscle
|
| gptkbp:complication |
gptkb:atrial_fibrillation
stroke |
| gptkbp:diagnosedBy |
electrocardiogram
echocardiogram cardiac MRI |
| gptkbp:differentialDiagnosis |
aortic stenosis
hypertensive heart disease athlete's heart |
| gptkbp:firstDescribed |
1958
|
| https://www.w3.org/2000/01/rdf-schema#label |
Hypertrophic cardiomyopathy
|
| gptkbp:ICD-10_code |
I42.1
|
| gptkbp:inheritance |
autosomal dominant
|
| gptkbp:MeSH_ID |
D006391
|
| gptkbp:mortalityRate |
about 1% per year
|
| gptkbp:mutationAssociatedWith |
gptkb:MYH7
TNNI3 TNNT2 TPM1 MYL2 MYL3 MYBPC3 ACTC1 |
| gptkbp:OMIM |
192600
|
| gptkbp:prevalence |
1 in 500 people
|
| gptkbp:prognosis |
variable
|
| gptkbp:riskFactor |
family history
genetic disorder |
| gptkbp:subspecies |
non-obstructive hypertrophic cardiomyopathy
obstructive hypertrophic cardiomyopathy |
| gptkbp:symptom |
fatigue
palpitations |
| gptkbp:treatment |
gptkb:implantable_cardioverter-defibrillator
beta blockers calcium channel blockers septal myectomy alcohol septal ablation |
| gptkbp:bfsParent |
gptkb:Echocardiography
|
| gptkbp:bfsLayer |
7
|