Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
|
| gptkbp:alsoKnownAs |
1,3-dipolar cycloaddition
|
| gptkbp:application |
click chemistry
organic synthesis |
| gptkbp:catalyzes |
ruthenium
copper(I) (CuAAC) |
| gptkbp:category |
gptkb:chemical_compound
pericyclic reaction |
| gptkbp:discoveredIn |
1960s
|
| gptkbp:example |
azide-alkyne cycloaddition
|
| https://www.w3.org/2000/01/rdf-schema#label |
Huisgen cycloaddition
|
| gptkbp:importantFor |
drug discovery
bioorthogonal chemistry |
| gptkbp:mechanismOfAction |
concerted
|
| gptkbp:namedAfter |
gptkb:Rolf_Huisgen
|
| gptkbp:productType |
five-membered heterocycle
|
| gptkbp:reactant |
1,3-dipole
dipolarophile |
| gptkbp:regioselectivity |
can be controlled by catalyst
|
| gptkbp:type |
cycloaddition
|
| gptkbp:yield |
gptkb:isoxazole
1,2,3-triazole pyrazoline |
| gptkbp:bfsParent |
gptkb:Rolf_Huisgen
|
| gptkbp:bfsLayer |
6
|