Statements (75)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
cell line
|
| gptkbp:are |
customizable
available for purchase widely used in academia used in regenerative medicine used in gene therapy research used in translational research used to explore therapeutic targets critical for pathway analysis essential for functional assays important for drug resistance studies important for personalized medicine important for synthetic biology important for understanding cellular mechanisms important for understanding gene networks integral to systems biology key tools for researchers part of gene editing advancements part of gene knockout technology used in cell biology used in molecular biology research used in pharmaceutical industry used in pharmacogenomics research used to explore cellular pathways used to investigate cellular aging used to model complex diseases used to model genetic diseases used to study cancer biology used to study gene interactions used to study gene therapy efficacy used to study metabolic pathways used to study stem cell differentiation valuable for functional assays |
| gptkbp:availableIn |
various human and mouse cell types
|
| gptkbp:canBe |
gene essentiality
|
| gptkbp:canLeadTo |
clinical trials
environmental research cancer research neuroscience research immune responses cellular differentiation toxicology studies cellular signaling. |
| gptkbp:characterizedBy |
CRISPR technology
|
| gptkbp:developedBy |
gptkb:Horizon_Discovery
|
| gptkbp:enables |
target validation
|
| gptkbp:facilitates |
functional genomics
|
| https://www.w3.org/2000/01/rdf-schema#label |
Horizon Knockout Cell Lines
|
| gptkbp:includes |
knockout of specific genes
|
| gptkbp:isCounteredBy |
genomic sequencing
|
| gptkbp:isIncorporatedIn |
cellular stress responses
|
| gptkbp:isMaintainedBy |
gene editing
|
| gptkbp:isSuitableFor |
specific research needs
|
| gptkbp:isUsedBy |
cell signaling pathways
|
| gptkbp:isUsedFor |
clinical research
high-throughput screening therapeutic development vaccine development biological assays in vitro experiments validate drug targets biomarker_discovery |
| gptkbp:isUtilizedFor |
cellular metabolism
gene regulation therapeutic strategies pathogen interactions cellular responses drug metabolism |
| gptkbp:mayHave |
protein interactions
|
| gptkbp:originatesFrom |
various sources
|
| gptkbp:provides |
validated knockout models
|
| gptkbp:supports |
biomedical research
|
| gptkbp:usedFor |
gene function studies
|
| gptkbp:usedIn |
drug_discovery
|
| gptkbp:works |
understand disease mechanisms
|