Hereditary spastic paraplegia
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
neurological disorder |
| gptkbp:affects |
corticospinal tract
|
| gptkbp:alsoKnownAs |
gptkb:Strümpell-Lorrain_disease
gptkb:familial_spastic_paraparesis |
| gptkbp:causedBy |
genetic disorder
|
| gptkbp:hasOrphanetID |
gptkb:ORPHA:215
|
| https://www.w3.org/2000/01/rdf-schema#label |
Hereditary spastic paraplegia
|
| gptkbp:ICD-10_code |
G11.4
|
| gptkbp:inheritance |
autosomal dominant
autosomal recessive X-linked |
| gptkbp:namedAfter |
gptkb:Adolf_Strümpell
gptkb:Maurice_Lorrain |
| gptkbp:OMIM |
182600
|
| gptkbp:onset |
childhood
adulthood |
| gptkbp:prevalence |
rare
|
| gptkbp:subspecies |
gptkb:SPG4
gptkb:SPG3A gptkb:SPG7 |
| gptkbp:symptom |
progressive weakness
difficulty walking spasticity of the legs |
| gptkbp:treatment |
physical therapy
mobility aids medications for spasticity |
| gptkbp:bfsParent |
gptkb:HSP
|
| gptkbp:bfsLayer |
5
|