| gptkbp:instanceOf | gptkb:vaccine 
 | 
                        
                            
                                | gptkbp:administeredBy | birth 6-18 months
 1-2 months
 
 | 
                        
                            
                                | gptkbp:approvedBy | gptkb:World_Health_Organization gptkb:U.S._Food_and_Drug_Administration
 1981
 
 | 
                        
                            
                                | gptkbp:boosterRecommended | no (for most people) 
 | 
                        
                            
                                | gptkbp:brand | gptkb:Recombivax_HB gptkb:Engerix-B
 gptkb:Heplisav-B
 gptkb:Twinrix
 
 | 
                        
                            
                                | gptkbp:broadcastOn | 3 doses 
 | 
                        
                            
                                | gptkbp:category | public health immunization
 infectious disease prevention
 
 | 
                        
                            
                                | gptkbp:combines | gptkb:Hepatitis_A_vaccine 
 | 
                        
                            
                                | gptkbp:contains | hepatitis B surface antigen 
 | 
                        
                            
                                | gptkbp:contraindication | severe allergic reaction to previous dose 
 | 
                        
                            
                                | gptkbp:developedBy | gptkb:Maurice_Hilleman 
 | 
                        
                            
                                | gptkbp:durationOfImmunity | at least 20 years 
 | 
                        
                            
                                | gptkbp:includedIn | gptkb:WHO_Essential_Medicines_List 
 | 
                        
                            
                                | gptkbp:indication | adults infants
 healthcare workers
 people at risk of hepatitis B infection
 
 | 
                        
                            
                                | gptkbp:marketedAs | gptkb:Sanofi_Pasteur gptkb:Merck_&_Co.
 gptkb:Dynavax_Technologies
 GlaxoSmithKline
 
 | 
                        
                            
                                | gptkbp:pregnancyCategory | safe 
 | 
                        
                            
                                | gptkbp:prevention | gptkb:Hepatitis_B 
 | 
                        
                            
                                | gptkbp:routeOfAdministration | intramuscular injection 
 | 
                        
                            
                                | gptkbp:sideEffect | fever fatigue
 soreness at injection site
 
 | 
                        
                            
                                | gptkbp:storage | 2-8°C 
 | 
                        
                            
                                | gptkbp:type | recombinant vaccine subunit vaccine
 
 | 
                        
                            
                                | gptkbp:WHOATCCode | gptkb:J07BC01 
 | 
                        
                            
                                | gptkbp:bfsParent | gptkb:Immunization_Clinic 
 | 
                        
                            
                                | gptkbp:bfsLayer | 7 
 | 
                        
                            
                                | https://www.w3.org/2000/01/rdf-schema#label | Hepatitis B Vaccine 
 |