|
gptkbp:instanceOf
|
hemoglobin-based oxygen carrier
|
|
gptkbp:activeIngredient
|
bovine hemoglobin
|
|
gptkbp:alsoKnownAs
|
gptkb:HBOC-201
|
|
gptkbp:alternativeTo
|
red blood cell transfusion
|
|
gptkbp:approvedBy
|
gptkb:South_Africa
2001
|
|
gptkbp:clinicalTrialPhase
|
investigational in many countries
|
|
gptkbp:color
|
dark red
|
|
gptkbp:compatibleWith
|
gptkb:European_Union
gptkb:United_States
|
|
gptkbp:contraindication
|
known hypersensitivity to bovine products
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Hemopure
|
|
gptkbp:indication
|
treatment of acute anemia
when blood transfusion is not an option
|
|
gptkbp:manufacturer
|
gptkb:Hemoglobin_Oxygen_Therapeutics_LLC
|
|
gptkbp:molecularSource
|
purified from cow blood
|
|
gptkbp:molecularWeight
|
~250 kDa
|
|
gptkbp:notDerivedFrom
|
human blood
|
|
gptkbp:osmolarity
|
250-350 mOsm/L
|
|
gptkbp:pH
|
7.4
|
|
gptkbp:routeOfAdministration
|
intravenous
|
|
gptkbp:shelfLife
|
up to 3 years
|
|
gptkbp:sideEffect
|
gptkb:methemoglobinemia
fever
hypertension
jaundice
chills
hemoglobinuria
|
|
gptkbp:storage
|
room temperature
|
|
gptkbp:usedFor
|
blood substitute
oxygen delivery
|
|
gptkbp:usedIn
|
Jehovah's Witness patients (in some cases)
|
|
gptkbp:bfsParent
|
gptkb:Blood_Substitute
|
|
gptkbp:bfsLayer
|
7
|