Helicobacter pylori CagA system
GPTKB entity
Statements (21)
Predicate | Object |
---|---|
gptkbp:instanceOf |
bacterial type IV secretion system
|
gptkbp:activatedBy |
host cell signaling pathways
|
gptkbp:amendedBy |
host cell junctions
|
gptkbp:associatedWith |
gptkb:peptic_ulcer_disease
gastric cancer |
gptkbp:cause |
cell elongation phenotype
cytoskeletal rearrangements |
gptkbp:composedOf |
VirB proteins
VirD4 protein |
gptkbp:encodedBy |
cag pathogenicity island
|
gptkbp:foundIn |
gptkb:Helicobacter_pylori
|
https://www.w3.org/2000/01/rdf-schema#label |
Helicobacter pylori CagA system
|
gptkbp:inducedBy |
inflammation
IL-8 secretion |
gptkbp:inhibitedBy |
apoptosis in host cells
|
gptkbp:interactsWith |
host epithelial cells
|
gptkbp:medium |
CagA translocation into host cells
|
gptkbp:requires |
gptkb:ATP
|
gptkbp:transportation |
CagA protein
|
gptkbp:bfsParent |
gptkb:type_IV_secretion_system
|
gptkbp:bfsLayer |
8
|