Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
physical phenomenon
|
| gptkbp:alsoKnownAs |
Hayflick phenomenon
|
| gptkbp:appliesTo |
normal somatic cells
|
| gptkbp:causedBy |
telomere shortening
|
| gptkbp:compatibleWith |
stem cells
cancer cells |
| gptkbp:describes |
the number of times a normal human cell population will divide before cell division stops
|
| gptkbp:discoveredBy |
gptkb:Leonard_Hayflick
|
| gptkbp:discoveredIn |
1961
|
| https://www.w3.org/2000/01/rdf-schema#label |
Hayflick limit
|
| gptkbp:influenced |
cancer biology
research on aging |
| gptkbp:opposedBy |
earlier belief that cells are immortal in culture
|
| gptkbp:publishedIn |
Experimental Cell Research
|
| gptkbp:relatedTo |
apoptosis
aging cellular senescence telomeres immortalization |
| gptkbp:significance |
limits the replicative potential of cells
|
| gptkbp:typicalValue |
40 to 60 cell divisions
|
| gptkbp:bfsParent |
gptkb:telomere_theory_of_aging
gptkb:telomere_theory |
| gptkbp:bfsLayer |
7
|