Hallervorden–Spatz disease

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:neurodegenerative_disease
gptkbp:abbreviation	gptkb:PKAN
gptkbp:affects	gptkb:basal_ganglia
gptkbp:alsoKnownAs	gptkb:Pantothenate_kinase-associated_neurodegeneration
gptkbp:category	gptkb:neurodegeneration_with_brain_iron_accumulation
gptkbp:characterizedBy	progressive movement disorder iron accumulation in the brain
gptkbp:controversy	eponym discouraged due to Nazi associations
gptkbp:firstDescribed	gptkb:Julius_Hallervorden gptkb:Hugo_Spatz 1922
gptkbp:hasOrphanetID	gptkb:ORPHA:211
gptkbp:ICD-10_code	gptkb:G23.0
gptkbp:inheritance	autosomal recessive
gptkbp:MRICharacteristic	gptkb:eye-of-the-tiger_sign
gptkbp:mutationAssociatedWith	gptkb:PANK2_gene
gptkbp:namedAfter	gptkb:Julius_Hallervorden gptkb:Hugo_Spatz
gptkbp:OMIM	234200
gptkbp:symptom	cognitive decline spasticity dystonia parkinsonism dysarthria
gptkbp:treatment	symptomatic management
gptkbp:bfsParent	gptkb:Julius_Hallervorden
gptkbp:bfsLayer	7
http://www.w3.org/2000/01/rdf-schema#label	Hallervorden–Spatz disease