HLH-2004 criteria

GPTKB entity

Statements (22)
Predicate Object
gptkbp:instanceOf diagnosis
gptkbp:appliesTo adult patients
pediatric patients
gptkbp:basisFor clinical diagnosis of HLH
clinical trials in HLH
gptkbp:criteria 8
fever
splenomegaly
cytopenias
elevated soluble CD25 (sIL-2 receptor)
ferritin elevation
hemophagocytosis
hypertriglyceridemia and/or hypofibrinogenemia
low or absent NK cell activity
gptkbp:diagnosisRequires 5 out of 8 criteria
https://www.w3.org/2000/01/rdf-schema#label HLH-2004 criteria
gptkbp:publishedBy Histiocyte Society
gptkbp:publishedIn 2004
gptkbp:replacedBy HLH-1994 criteria
gptkbp:usedFor diagnosis of hemophagocytic lymphohistiocytosis
gptkbp:bfsParent gptkb:HLH
gptkbp:bfsLayer 8