Statements (58)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:monoclonal_antibody
|
| gptkbp:associated_with |
gptkb:disease
gptkb:ankylosing_spondylitis gptkb:psoriatic_arthritis gptkb:reactive_arthritis uveitis |
| gptkbp:can_detect |
serological testing
DNA typing |
| gptkbp:code |
B27 gene
|
| gptkbp:discovered_by |
Jean Dausset
|
| gptkbp:has_influence_on |
disease severity
|
| https://www.w3.org/2000/01/rdf-schema#label |
HLA-B27 antigen
|
| gptkbp:influences |
immune response
|
| gptkbp:is_a |
class I MHC molecule
|
| gptkbp:is_associated_with |
chronic inflammatory diseases
dermatological manifestations cardiac involvement dactylitis axial spondyloarthritis enthesitis neurological manifestations ocular manifestations pulmonary involvement renal involvement sacroiliitis systemic involvement |
| gptkbp:is_expressed_in |
cell surface
|
| gptkbp:is_found_in |
blood samples
human leukocytes |
| gptkbp:is_involved_in |
gptkb:disease
metabolic disorders psychological disorders T cell activation musculoskeletal disorders transplant rejection respiratory disorders endocrine disorders gastrointestinal disorders neuropsychiatric disorders pathogenesis of diseases cardiovascular disorders immune-mediated diseases chronic pain syndromes chronic inflammatory response dermatological disorders fatigue syndromes |
| gptkbp:is_linked_to |
gptkb:juvenile_idiopathic_arthritis
autoimmune diseases |
| gptkbp:is_recognized_as |
1970s
|
| gptkbp:is_related_to |
HLA system
|
| gptkbp:is_studied_in |
genetic research
|
| gptkbp:is_tested_for |
diagnosis of diseases
|
| gptkbp:part_of |
major histocompatibility complex
|
| gptkbp:prevalence |
African populations
Asian populations Northern European populations |
| gptkbp:bfsParent |
gptkb:ankylosing_spondylitis
|
| gptkbp:bfsLayer |
6
|