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gptkbp:instanceOf
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gptkb:Dragon
gptkb:chemical_compound
|
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gptkbp:affects
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gptkb:nervous_system
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gptkbp:category
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gptkb:Dragon
diterpene
plant toxin
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gptkbp:cause
|
mad honey poisoning
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gptkbp:chemicalFormula
|
C15H24O6
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gptkbp:compatibleWith
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gptkb:medicine
|
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gptkbp:discoveredBy
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gptkb:Y._Okamoto
|
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gptkbp:discoveredIn
|
1912
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gptkbp:foundIn
|
gptkb:Kalmia_species
gptkb:Pieris_species
Rhododendron species
plants of the Ericaceae family
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|
https://www.w3.org/2000/01/rdf-schema#label
|
Grayanotoxin
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gptkbp:mechanismOfAction
|
binds to voltage-gated sodium channels
|
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gptkbp:otherName
|
gptkb:acetylandromedol
gptkb:andromedotoxin
gptkb:rhodotoxin
|
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gptkbp:solubility
|
soluble in water
|
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gptkbp:source
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gptkb:mad_honey
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gptkbp:symptom
|
gptkb:arrhythmia
nausea
vomiting
dizziness
salivation
blurred vision
sweating
hypotension
bradycardia
loss of coordination
seizures (rare)
|
|
gptkbp:toxicity
|
toxic to humans and animals
|
|
gptkbp:treatment
|
gptkb:atropine_(for_bradycardia)
supportive care
IV fluids
|
|
gptkbp:usedIn
|
toxicology research
|
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gptkbp:bfsParent
|
gptkb:Azalea
|
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gptkbp:bfsLayer
|
4
|