Glomerular Filtration Barrier
GPTKB entity
Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:anatomical_structure
|
| gptkbp:associatedWith |
nephrotic syndrome
|
| gptkbp:composedOf |
glomerular basement membrane
fenestrated endothelium podocyte foot processes |
| gptkbp:criteria |
charge selective
size selective |
| gptkbp:damageCauses |
hematuria
proteinuria |
| gptkbp:discoveredBy |
gptkb:Franz_Volhard
|
| gptkbp:function |
filtration of blood plasma
|
| https://www.w3.org/2000/01/rdf-schema#label |
Glomerular Filtration Barrier
|
| gptkbp:layer |
glomerular basement membrane
fenestrated endothelium podocyte slit diaphragm |
| gptkbp:locatedIn |
gptkb:kidney
|
| gptkbp:partOf |
renal corpuscle
|
| gptkbp:permits |
passage of small solutes
passage of water |
| gptkbp:prohibits |
passage of blood cells
passage of proteins |
| gptkbp:relatedTo |
gptkb:minimal_change_disease
diabetic nephropathy nephrotic syndrome focal segmental glomerulosclerosis |
| gptkbp:thickness |
approximately 300-350 nm
|
| gptkbp:bfsParent |
gptkb:GFB
|
| gptkbp:bfsLayer |
7
|