Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:Cellular_structure
|
| gptkbp:alternativeName |
gptkb:Nexus
Communicating junction |
| gptkbp:associatedWith |
gptkb:Charcot-Marie-Tooth_disease
gptkb:Cardiac_arrhythmia Deafness |
| gptkbp:compatibleWith |
Plant cells
|
| gptkbp:composedOf |
Connexins
|
| gptkbp:discoveredBy |
Jean-Paul Revel
M. J. Karnovsky |
| gptkbp:doesNotPermit |
Passage of large proteins
Passage of nucleic acids |
| gptkbp:firstDescribed |
1967
|
| gptkbp:foundIn |
Animal cells
|
| gptkbp:function |
Cell-cell communication
Electrical coupling Metabolic coupling |
| gptkbp:permits |
Passage of ions
Passage of small molecules |
| gptkbp:presentIn |
Cardiac muscle
Smooth muscle Nervous tissue |
| gptkbp:proteinFamily |
gptkb:GJA1
GJB2 GJC1 |
| gptkbp:regulates |
pH
Calcium ions |
| gptkbp:relatedTo |
gptkb:Plasmodesmata
|
| gptkbp:structure |
Hexameric connexon
Two connexons form a channel |
| gptkbp:bfsParent |
gptkb:Membrane_Channels
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
Gap Junction
|