Gap Junction

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf Cellular structure
gptkbp:alternativeName gptkb:Nexus
Communicating junction
gptkbp:associatedWith gptkb:Charcot-Marie-Tooth_disease
Cardiac arrhythmia
Deafness
gptkbp:compatibleWith Plant cells
gptkbp:composedOf Connexins
gptkbp:discoveredBy Jean-Paul Revel
M. J. Karnovsky
gptkbp:doesNotPermit Passage of large proteins
Passage of nucleic acids
gptkbp:firstDescribed 1967
gptkbp:foundIn Animal cells
gptkbp:function Cell-cell communication
Electrical coupling
Metabolic coupling
https://www.w3.org/2000/01/rdf-schema#label Gap Junction
gptkbp:permits Passage of ions
Passage of small molecules
gptkbp:presentIn Cardiac muscle
Smooth muscle
Nervous tissue
gptkbp:proteinFamily gptkb:GJA1
GJB2
GJC1
gptkbp:regulates pH
Calcium ions
gptkbp:relatedTo gptkb:Plasmodesmata
gptkbp:structure Hexameric connexon
Two connexons form a channel
gptkbp:bfsParent gptkb:Membrane_Channels
gptkbp:bfsLayer 7