Statements (33)
Predicate | Object |
---|---|
gptkbp:instanceOf |
Cellular structure
|
gptkbp:alternativeName |
gptkb:Nexus
Communicating junction |
gptkbp:associatedWith |
gptkb:Charcot-Marie-Tooth_disease
Cardiac arrhythmia Deafness |
gptkbp:compatibleWith |
Plant cells
|
gptkbp:composedOf |
Connexins
|
gptkbp:discoveredBy |
Jean-Paul Revel
M. J. Karnovsky |
gptkbp:doesNotPermit |
Passage of large proteins
Passage of nucleic acids |
gptkbp:firstDescribed |
1967
|
gptkbp:foundIn |
Animal cells
|
gptkbp:function |
Cell-cell communication
Electrical coupling Metabolic coupling |
https://www.w3.org/2000/01/rdf-schema#label |
Gap Junction
|
gptkbp:permits |
Passage of ions
Passage of small molecules |
gptkbp:presentIn |
Cardiac muscle
Smooth muscle Nervous tissue |
gptkbp:proteinFamily |
gptkb:GJA1
GJB2 GJC1 |
gptkbp:regulates |
pH
Calcium ions |
gptkbp:relatedTo |
gptkb:Plasmodesmata
|
gptkbp:structure |
Hexameric connexon
Two connexons form a channel |
gptkbp:bfsParent |
gptkb:Membrane_Channels
|
gptkbp:bfsLayer |
7
|