Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
|
| gptkbp:category |
name reaction
organic chemistry reaction |
| gptkbp:compatibleWith |
tertiary amine
secondary amine |
| gptkbp:firstReported |
1887
|
| https://www.w3.org/2000/01/rdf-schema#label |
Gabriel synthesis
|
| gptkbp:hydrolysisMethod |
acidic hydrolysis
basic hydrolysis |
| gptkbp:limitation |
not suitable for aryl halides
not suitable for secondary alkyl halides |
| gptkbp:mechanismOfAction |
nucleophilic substitution
|
| gptkbp:namedAfter |
Siegmund Gabriel
|
| gptkbp:produces |
primary amine
|
| gptkbp:step |
formation of N-alkylphthalimide
hydrolysis of N-alkylphthalimide |
| gptkbp:type |
substitution reaction
|
| gptkbp:usedFor |
synthesis of primary amines
|
| gptkbp:usesReagent |
gptkb:foundation
alkyl halide phthalimide |
| gptkbp:bfsParent |
gptkb:Strecker_amino_acid_synthesis
|
| gptkbp:bfsLayer |
7
|