Statements (53)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic study
|
| gptkbp:aimsToIdentify |
associations between genetic variants and traits
|
| gptkbp:analyzes |
single-nucleotide polymorphisms
|
| gptkbp:associatedWith |
quantitative traits
complex diseases |
| gptkbp:firstPublished |
2005
|
| gptkbp:fullName |
Genome-Wide Association Study
|
| https://www.w3.org/2000/01/rdf-schema#label |
GWAS
|
| gptkbp:limitation |
population stratification
missing heritability multiple testing burden |
| gptkbp:output |
p-values
effect sizes Manhattan plot |
| gptkbp:publishedIn |
gptkb:Nature
gptkb:science gptkb:Nature_Genetics PLoS Genetics |
| gptkbp:regulates |
informed consent
ethical guidelines |
| gptkbp:relatedTo |
functional genomics
linkage disequilibrium candidate gene study fine mapping polygenic risk score |
| gptkbp:requires |
statistical analysis
quality control large sample sizes replication studies |
| gptkbp:studies |
genetic variants
|
| gptkbp:supportedBy |
bioinformatics
genotyping arrays whole-genome sequencing |
| gptkbp:supportsDatabase |
gptkb:GWAS_Catalog
gptkb:dbGaP gptkb:1000_Genomes_Project gptkb:UK_Biobank Biobank Japan FinnGen |
| gptkbp:usedFor |
population genetics
personalized medicine evolutionary studies drug target discovery disease risk prediction |
| gptkbp:usedIn |
human genetics
plant genetics animal genetics |
| gptkbp:uses |
case-control design
cohort design |
| gptkbp:bfsParent |
gptkb:SAIGE
gptkb:JMP_Genomics gptkb:Illumina_BeadArray |
| gptkbp:bfsLayer |
8
|