GTN

GPTKB entity

Properties (46)
Predicate Object
gptkbp:instanceOf chemical compound
gptkbp:armament highly explosive
gptkbp:availableFormats intravenous infusion
transdermal patches
oral spray
gptkbp:chemicalFormula requires careful handling
C3H5N3O9
trinitrate_ester
gptkbp:constructedIn 1847
gptkbp:contraindication hypotension
increased intracranial pressure
severe anemia
gptkbp:culturalHeritage featured in literature and film.
gptkbp:dissolved slightly soluble
gptkbp:environmental_impact toxic to aquatic life
gptkbp:established gptkb:Ascanio_Sobrero
gptkbp:historical_significance used_in_World_War_I_and_II
https://www.w3.org/2000/01/rdf-schema#label GTN
gptkbp:iceClass 13 °C
x °C (decomposes)
gptkbp:impact dizziness
headache
nausea
gptkbp:is_used_in palliative care
sports medicine
heart failure treatment
dynamite production
treatment of angina pectoris
vasodilator
acute_coronary_syndrome_treatment
gptkbp:marketedAs various brand names
gptkbp:origin glyceryl trinitrate
gptkbp:patentStatus generic availability
gptkbp:previousName nitroglycerin
gptkbp:produces nitric oxide
gptkbp:regulatoryCompliance approved_by_FDA
approved_by_EMA
gptkbp:related_to amyl nitrite
isosorbide dinitrate
isosorbide mononitrate
gptkbp:researchInterest studied for potential cancer treatment
studied for potential neuroprotective effects
gptkbp:safety_features explosive and flammable
gptkbp:storage cool, dry place
gptkbp:triggerType relaxes vascular smooth muscle
gptkbp:utilizes sublingual tablets