Statements (31)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:drug
|
gptkbp:approvalYear |
2012
|
gptkbp:ATCCode |
N03AX22
|
gptkbp:CASNumber |
380917-97-5
|
gptkbp:chemicalFormula |
C23H15N3O
|
gptkbp:drugClass |
anticonvulsant
|
gptkbp:eliminationHalfLife |
105 hours
|
gptkbp:excretion |
urine
feces |
gptkbp:genericName |
gptkb:perampanel
|
https://www.w3.org/2000/01/rdf-schema#label |
Fycompa
|
gptkbp:legalStatus |
prescription only
|
gptkbp:manufacturer |
gptkb:Eisai
|
gptkbp:mechanismOfAction |
AMPA receptor antagonist
|
gptkbp:metabolism |
liver (CYP3A4/5)
|
gptkbp:pregnancyCategory |
C (US)
|
gptkbp:proteinBinding |
95-96%
|
gptkbp:routeOfAdministration |
oral
|
gptkbp:sideEffect |
dizziness
aggression gait disturbance irritability somnolence |
gptkbp:status |
FDA approved
EMA approved |
gptkbp:usedFor |
epilepsy
partial-onset seizures primary generalized tonic-clonic seizures |
gptkbp:bfsParent |
gptkb:Eisai_Co.,_Ltd.
gptkb:Eisai |
gptkbp:bfsLayer |
6
|