Frank-Starling law of the heart

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf physiological principle
gptkbp:alsoKnownAs gptkb:Frank-Starling_mechanism
gptkb:Starling's_law
gptkbp:appliesTo heart
gptkbp:category cardiology
physiology
gptkbp:describes relationship between stroke volume and end-diastolic volume
gptkbp:explains intrinsic regulation of cardiac output
gptkbp:firstDescribed early 20th century
https://www.w3.org/2000/01/rdf-schema#label Frank-Starling law of the heart
gptkbp:importantFor adaptation of the heart to changing venous return
gptkbp:mechanismOfAction increased venous return stretches ventricular wall, causing cardiac muscle to contract more forcefully
gptkbp:namedAfter gptkb:Ernest_Starling
gptkb:Otto_Frank
gptkbp:relatedTo cardiac physiology
preload
cardiac output
end-diastolic volume
myocardial contractility
stroke volume
gptkbp:state the stroke volume of the heart increases in response to an increase in the volume of blood filling the heart
gptkbp:bfsParent gptkb:Ernest_Starling
gptkbp:bfsLayer 5