Fractionated radiotherapy

GPTKB entity

Statements (49)
Predicate Object
gptkbp:instanceOf Radiotherapy technique
gptkbp:administeredOver Several days or weeks
gptkbp:alternativeTo Surgery
Chemotherapy
Single-fraction radiotherapy
gptkbp:appliesTo Brain tumors
Head and neck cancers
Prostate cancer
Breast cancer
Solid tumors
gptkbp:benefit Allows normal tissue repair
Improves therapeutic ratio
gptkbp:contraindication gptkb:Pregnancy
Severe comorbidities
gptkbp:contrastsWith Single-dose radiotherapy
gptkbp:deliveredBy Linear accelerator
Cobalt-60 machine
gptkbp:developedBy Henri Coutard
gptkbp:doseUnit gptkb:Gray_(Gy)
gptkbp:fractionSize 1.8-2 Gy per fraction (conventional)
gptkbp:goal Maximize tumor dose
Minimize normal tissue exposure
https://www.w3.org/2000/01/rdf-schema#label Fractionated radiotherapy
gptkbp:introducedIn 1920s
gptkbp:method Divides total radiation dose into multiple smaller doses
gptkbp:monitors Medical physicist
Radiation oncologist
Radiation therapist
gptkbp:purpose Increase tumor control
Reduce side effects
gptkbp:regulates Radiation oncology guidelines
gptkbp:relatedTo Conformal radiotherapy
Intensity-modulated radiotherapy
Stereotactic radiotherapy
gptkbp:requires Imaging studies
Treatment planning
gptkbp:reviewedBy gptkb:National_Comprehensive_Cancer_Network
gptkb:American_Society_for_Radiation_Oncology
gptkbp:sideEffect gptkb:Nausea
Fatigue
Hair loss
Skin irritation
gptkbp:subspecies Accelerated fractionation
Hyperfractionation
Hypofractionation
gptkbp:totalDose Varies by cancer type
gptkbp:usedIn Cancer treatment
gptkbp:bfsParent gptkb:Biological_Effective_Dose
gptkbp:bfsLayer 7