Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
medical condition
|
| gptkbp:abbreviation |
Fragile X-associated primary ovarian insufficiency
|
| gptkbp:affects |
female
ovaries |
| gptkbp:category |
genetic disorder
reproductive disorder |
| gptkbp:causedBy |
FMR1 gene premutation
FMR1 gene CGG repeat expansion |
| gptkbp:diagnosedBy |
genetic testing
hormone level tests |
| gptkbp:firstDescribed |
1990s
|
| gptkbp:fullName |
Fragile X-associated primary ovarian insufficiency
|
| https://www.w3.org/2000/01/rdf-schema#label |
FXPOI
|
| gptkbp:ICD-10_code |
E28.319
|
| gptkbp:MeSH_ID |
D000328
|
| gptkbp:OMIM |
300623
|
| gptkbp:prevalence |
affects about 20% of women with FMR1 premutation
|
| gptkbp:relatedTo |
gptkb:Fragile_X_syndrome
Fragile X-associated tremor/ataxia syndrome |
| gptkbp:riskFactor |
female carriers of FMR1 premutation
|
| gptkbp:symptom |
infertility
night sweats hot flashes amenorrhea oligomenorrhea irregular menstrual cycles decreased estrogen levels early menopause osteoporosis risk vasomotor symptoms |
| gptkbp:treatment |
hormone replacement therapy
fertility counseling |
| gptkbp:bfsParent |
gptkb:CGG
gptkb:fragile_X-associated_primary_ovarian_insufficiency |
| gptkbp:bfsLayer |
8
|