Evans aldol reaction

GPTKB entity

Statements (20)
Predicate Object
gptkbp:instanceOf gptkb:chemical_compound
gptkbp:advantage high enantioselectivity
high diastereoselectivity
gptkbp:application natural product synthesis
gptkbp:chiralAuxiliary gptkb:Evans_oxazolidinone
gptkbp:developedBy 1980s
gptkbp:enables stereoselective carbon-carbon bond formation
https://www.w3.org/2000/01/rdf-schema#label Evans aldol reaction
gptkbp:mechanismOfAction enolate addition
gptkbp:namedAfter gptkb:David_A._Evans
gptkbp:notableFor enantioselective synthesis
gptkbp:product β-hydroxy carbonyl compound
gptkbp:removalOfAuxiliary hydrolysis
gptkbp:substrate aldehyde
enolizable carbonyl compound
gptkbp:type gptkb:aldol_reaction
gptkbp:usedIn organic synthesis
gptkbp:uses chiral auxiliary
gptkbp:bfsParent gptkb:David_A._Evans
gptkbp:bfsLayer 6