Enhancer

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf DNA sequence
gptkbp:binds transcription factors
gptkbp:can_be_identified_by chromatin immunoprecipitation
reporter assays
gptkbp:can_be_marked_by H3K27ac
H3K4me1
gptkbp:canBe cis-regulatory element
cell-type specific
developmentally regulated
distal regulatory element
super-enhancer
gptkbp:directionA can function in either orientation
gptkbp:discoveredBy Banerji et al.
gptkbp:discoveredIn 1981
gptkbp:distanceFromGene can be thousands of base pairs away
gptkbp:foundIn eukaryotic genomes
gptkbp:function increases transcription of genes
https://www.w3.org/2000/01/rdf-schema#label Enhancer
gptkbp:interactsWith promoters
gptkbp:location can be upstream or downstream of gene
gptkbp:regulates gene expression
gptkbp:bfsParent gptkb:Ultima_Weapon
gptkbp:bfsLayer 5