Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
small molecule |
| gptkbp:approvedBy |
gptkb:FDA
gptkb:EMA 2019 |
| gptkbp:ATCCode |
gptkb:R07AX31
|
| gptkbp:CASNumber |
gptkb:2114140-23-9
|
| gptkbp:component |
gptkb:Kaftrio
gptkb:Trikafta |
| gptkbp:developedBy |
gptkb:Vertex_Pharmaceuticals
|
| gptkbp:hasMolecularFormula |
C26H32F2N2O6
|
| https://www.w3.org/2000/01/rdf-schema#label |
Elexacaftor
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
CFTR modulator
|
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
headache
rash upper respiratory tract infection increased liver enzymes |
| gptkbp:target |
gptkb:CFTR_protein
|
| gptkbp:usedFor |
cystic fibrosis
|
| gptkbp:bfsParent |
gptkb:CFTR
|
| gptkbp:bfsLayer |
7
|