Mycobacterium leprae

E928041

Mycobacterium leprae is a slow-growing, acid-fast bacterium that causes leprosy (Hansen’s disease) in humans.

All labels observed (4)

Label Occurrences
Mycobacterium leprae canonical 8
Hansen’s disease 1
Leprosy 1

How this entity was disambiguated

Statements (51)

Predicate Object
instanceOf acid-fast bacterium
bacterium
pathogen
acidFastComponent mycolic acids
antimicrobialSusceptibility clofazimine-sensitive
dapsone-sensitive
rifampicin-sensitive
cellEnvelopeComponent phenolic glycolipid-1
cellWallProperty acid-fast
clinicalAssociation borderline forms of leprosy
lepromatous leprosy
tuberculoid leprosy
cultureProperty can be propagated in armadillo
can be propagated in mouse footpad
not cultivable on standard artificial media
discoveredBy Gerhard Armauer Hansen
diseaseCaused Hansen’s disease
leprosy
domain Bacteria
doublingTime about 12 to 14 days
family Mycobacteriaceae
genomeFeature high proportion of pseudogenes
reductive evolution
genomeSize approximately 3.3 Mb
genomeType circular chromosome
double-stranded DNA
genus Mycobacterium
gramStain Gram-positive
growthRate slow-growing
immuneEvasionMechanism modulation of cell-mediated immunity
survival in macrophages
optimalTemperature cooler body sites
order Corynebacteriales
oxygenRequirement aerobic
phylum Actinobacteria
preferredTissue peripheral nerves
skin
primaryHost human
publicHealthRelevance neglected tropical disease agent
shape rod-shaped
stain Fite-Faraco positive
Ziehl–Neelsen positive
taxonRank species
transmissionRoute prolonged close contact
respiratory droplets
tropism Schwann cells
peripheral nerves
skin macrophages
yearDiscovered 1873
zoonoticReservoir nine-banded armadillo
red squirrel

How these facts were elicited

Referenced by (11)

Full triples — surface form annotated when it differs from this entity's canonical label.

Mycobacterium includesSpecies Mycobacterium leprae
Corynebacteriales includesPathogen Mycobacterium leprae
Ziehl–Neelsen stain detectsOrganism Mycobacterium leprae
Actinobacteria includesPathogen Mycobacterium leprae
Kalawao associatedWithDisease Hansen’s disease
linked to: Mycobacterium leprae
Chuck Schuldiner notableAlbumWithDeath Leprosy
linked to: Mycobacterium leprae
Mycobacteriales includesPathogenicTaxa Mycacterium leprae
linked to: Mycobacterium leprae
Mycobacteriaceae includesPathogen Mycobacterium leprae
Mycobacteriaceae containsSpecies Mycobacterium leprae
Mycobacterium ulcerans relatedPathogen Mycobacterium leprae
ZN stain detects Mycobacterium leprae