JC virus
E559470
JC virus is a human polyomavirus that typically causes asymptomatic infection but can lead to severe demyelinating brain disease in immunocompromised individuals.
All labels observed (2)
How this entity was disambiguated
This entity first appeared as the object of triple T5981292 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: JC virus Context triple: [progressive multifocal leukoencephalopathy, hasPathogen, JC virus]
-
A.
EBV
EBV is the National Rail station code for Ebbw Vale Parkway railway station in Wales.
-
B.
KHV
KHV is the IATA airport code for Khabarovsk Novy Airport, a major air transport hub serving the city of Khabarovsk in Russia’s Far East.
-
C.
Ebolavirus
Ebolavirus is a genus of filamentous, enveloped RNA viruses in the Filoviridae family that cause severe and often fatal hemorrhagic fever in humans and other primates.
-
D.
MHV
MHV is the IATA airport code for Mojave Air and Space Port, a well-known aerospace testing and flight facility in Mojave, California.
-
E.
Vircava
Vircava is a river in Latvia that serves as one of the tributaries feeding into the larger Lielupe River system.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: JC virus Target entity description: JC virus is a human polyomavirus that typically causes asymptomatic infection but can lead to severe demyelinating brain disease in immunocompromised individuals.
-
A.
EBV
EBV is the National Rail station code for Ebbw Vale Parkway railway station in Wales.
-
B.
KHV
KHV is the IATA airport code for Khabarovsk Novy Airport, a major air transport hub serving the city of Khabarovsk in Russia’s Far East.
-
C.
Ebolavirus
Ebolavirus is a genus of filamentous, enveloped RNA viruses in the Filoviridae family that cause severe and often fatal hemorrhagic fever in humans and other primates.
-
D.
MHV
MHV is the IATA airport code for Mojave Air and Space Port, a well-known aerospace testing and flight facility in Mojave, California.
-
E.
Vircava
Vircava is a river in Latvia that serves as one of the tributaries feeding into the larger Lielupe River system.
- F. None of above. chosen
Statements (55)
| Predicate | Object |
|---|---|
| instanceOf |
DNA virus
ⓘ
human polyomavirus ⓘ virus ⓘ |
| abbreviation |
JCV
ⓘ
linked to:
JC virus
|
| alsoKnownAs | John Cunningham virus ⓘ |
| associatedDisease | progressive multifocal leukoencephalopathy ⓘ |
| biosafetyLevel | 2 ⓘ |
| capsidSymmetry | icosahedral ⓘ |
| cellEntryReceptor | serotonin receptor 5-HT2A ⓘ |
| diagnosticMethod |
PCR of cerebrospinal fluid
ⓘ
brain MRI ⓘ brain biopsy ⓘ |
| discoveredBy |
Chou
ⓘ
ZuRhein ⓘ |
| discoveryYear | 1971 ⓘ |
| encodesProtein |
VP1
ⓘ
VP2 ⓘ VP3 ⓘ agnoprotein ⓘ large T antigen ⓘ small t antigen ⓘ |
| enveloped | no ⓘ |
| family | Polyomaviridae ⓘ |
| genomeSegment |
early region
ⓘ
late region ⓘ |
| genomeStructure | circular DNA ⓘ |
| genomeType | double-stranded DNA ⓘ |
| genus | Polyomavirus ⓘ |
| host |
Homo sapiens
ⓘ
human ⓘ |
| latencySite |
bone marrow
ⓘ
kidney ⓘ lymphoid tissue ⓘ |
| namedAfter | John Cunningham ⓘ |
| oncogenicPotential | possible ⓘ |
| pathology | demyelination ⓘ |
| prevalence | high seroprevalence in adults ⓘ |
| primaryInfectionOutcome | asymptomatic infection ⓘ |
| reactivationCondition | immunosuppression ⓘ |
| reactivationOutcome |
central nervous system infection
ⓘ
viremia ⓘ |
| riskGroup |
AIDS patients
ⓘ
immunocompromised individuals ⓘ organ transplant recipients ⓘ patients on natalizumab ⓘ patients on other immunosuppressive therapies ⓘ |
| seroprevalenceRange | 50-80% of adults ⓘ |
| targetOrgan | brain ⓘ |
| taxonRank | species ⓘ |
| transmissionRoute |
oral-fecal route
ⓘ
respiratory route ⓘ urinary route ⓘ |
| tropism |
astrocytes
ⓘ
kidney epithelial cells ⓘ oligodendrocytes ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: JC virus Description of subject: JC virus is a human polyomavirus that typically causes asymptomatic infection but can lead to severe demyelinating brain disease in immunocompromised individuals.
Referenced by (4)
Full triples — surface form annotated when it differs from this entity's canonical label.
linked to: JC virus
linked to: JC virus