respiratory syncytial virus (RSV)

E474952

Respiratory syncytial virus (RSV) is a common contagious virus that primarily infects the respiratory tract, especially in infants and older adults, and is a leading cause of bronchiolitis and pneumonia worldwide.

All labels observed (5)

Label Occurrences
respiratory syncytial virus 4
Human orthopneumovirus 1
RSV A 1

How this entity was disambiguated

Statements (69)

Predicate Object
instanceOf human pathogen
orthopneumovirus
virus
affectsAgeGroup immunocompromised individuals
infants
older adults
young children
associatedWithComplication apnea in young infants
respiratory failure
wheezing
associatedWithLongTermOutcome increased risk of asthma
recurrent wheezing in childhood
attachmentMediatedBy G protein
biosafetyLevel 2
causesDisease acute respiratory infection
bronchiolitis
lower respiratory tract infection
pneumonia
upper respiratory tract infection
diagnosedBy RT-PCR
antigen detection tests
viral culture
discoveredBy Robert M. Chanock
discoveredIn 1956
entryMediatedBy F protein
enveloped true
family Pneumoviridae
genus Orthopneumovirus
linked to: Pneumoviridae
globalBurden major cause of infant hospitalization worldwide
hasGenomeStructure nonsegmented genome
hasGenomeType negative-sense single-stranded RNA
hasProphylaxis nirsevimab
palivizumab
hasProtein F protein
G protein
L protein
M protein
M2 protein
N protein
P protein
SH protein
hasSerotype RSV A
RSV B
hasVaccine RSV prefusion F protein-based vaccines
incubationPeriod 2 to 8 days
isLeadingCauseOf bronchiolitis in infants
pneumonia in infants
majorHost humans
parentTaxon Human orthopneumovirus
preventedBy avoidance of close contact with infected individuals
hand hygiene
respiratory etiquette
primaryInfectionSite lower respiratory tract
upper respiratory tract
routeOfEntry conjunctival mucosa
nasal mucosa
seasonality early spring
winter
shape pleomorphic
taxonRank species
transmissionRoute direct contact with respiratory secretions
fomites
respiratory droplets
treatment mechanical ventilation in severe cases
oxygen therapy
supportive care
vaccineTargetGroup high-risk infants
older adults
pregnant women

How these facts were elicited

Referenced by (8)

Full triples — surface form annotated when it differs from this entity's canonical label.

MedImmune researchArea respiratory syncytial virus (RSV)
human adenovirus serotype 26 usedInVaccineAgainst respiratory syncytial virus
linked to: respiratory syncytial virus (RSV)
Mononegavirales notableHumanPathogensInclude respiratory syncytial virus
linked to: respiratory syncytial virus (RSV)
Synagis targets respiratory syncytial virus
linked to: respiratory syncytial virus (RSV)
respiratory syncytial virus parentTaxon Human orthopneumovirus
linked to: respiratory syncytial virus (RSV)
respiratory syncytial virus hasSerotype RSV A
linked to: respiratory syncytial virus (RSV)
respiratory syncytial virus hasSerotype RSV B
linked to: respiratory syncytial virus (RSV)
mRNA vaccine canTarget respiratory syncytial virus
linked to: respiratory syncytial virus (RSV)