Bicycle Therapeutics

E422484

Bicycle Therapeutics is a biotechnology company that develops novel therapeutics based on its proprietary bicyclic peptide (Bicycle®) platform, with a focus on targeted treatments for cancer and other serious diseases.

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Bicycle Therapeutics canonical 1

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Statements (49)

Predicate Object
instanceOf biotechnology company
public company
countryOfOrigin United Kingdom
develops Bicycle molecules
bicyclic peptide therapeutics
focusesOn cancer therapeutics
oncology
targeted therapies
foundedBy Christian Heinis
Gregory Winter
Ian Tomlinson
foundedInPeriod late 2000s
hasClinicalCandidate BT1718
BT5528
BT7480
BT8009
hasCollaboration AstraZeneca
Cancer Research UK
Ionis Pharmaceuticals
Novartis
hasIntellectualProperty proprietary Bicycle peptide platform
hasKeyPerson Kevin Lee
hasOffice Cambridge, Massachusetts, United States
hasTechnologyPlatform Bicycle peptide platform
hasTherapeuticArea other serious diseases
solid tumor cancers
headquartersLocation Cambridge, United Kingdom
linked to: Cambridge, England
industry biotechnology
mission to develop targeted therapeutics for cancer and other serious diseases
positionHeld Kevin Lee – Chief Executive Officer
researchArea hematologic malignancies
immuno-oncology
solid tumors
specializesIn bicyclic peptides
chemically constrained peptides
stockTicker BCYC
targets EphA2 (via BT5528)
MT1-MMP (via BT1718)
Nectin-4 (via BT8009)
Nectin-4/CD137 (via BT7480)
technologyCharacteristic high affinity target binding
rapid clearance from circulation
rapid tissue penetration
small, chemically synthesized peptides
tradesOn NASDAQ
usesApproach phage display for peptide discovery
usesModality tumor-targeted immune cell agonists
tumor-targeted radioconjugates
tumor-targeted toxin conjugates

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Cambridge life sciences ecosystem hasKeyCompany Bicycle Therapeutics