AlphaFold

E39542

AlphaFold is an artificial intelligence system developed by DeepMind that predicts protein 3D structures from amino acid sequences with unprecedented accuracy, revolutionizing structural biology.

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Generate an image of AlphaFold (AlphaFold is an artificial intelligence system developed by DeepMind that predicts protein 3D structures from amino acid sequences with unprecedented accuracy, revolutionizing structural biology.)

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Statements (50)

Predicate Object
instanceOf artificial intelligence system
protein structure prediction system
protein structure prediction system
achievement top performance in CASP13 protein structure prediction competition
top performance in CASP14 protein structure prediction competition
announced 2020
announcedAt CASP13
approach end-to-end differentiable learning
structure prediction from sequence alone
basedOn attention mechanisms
evolutionary information
multiple sequence alignments
transformer architecture
citation Jumper et al., Nature 2021
dataSource UniProt protein sequences
developer DeepMind
DeepMind
Google DeepMind
linked to: DeepMind
evaluationMetric GDT_TS
field bioinformatics
computational biology
structural biology
hostedOn EMBL-EBI AlphaFold Protein Structure Database
impact accelerated determination of protein structures
reduced need for experimental structure determination
input amino acid sequence
language Python
license open-source license
majorUpdate AlphaFold2
linked to: AlphaFold
notableFor high accuracy in protein structure prediction
near-experimental accuracy in protein structure prediction
revolutionizing structural biology
organization Alphabet Inc.
output protein 3D structure
parentOrganization DeepMind
published 2021
relatedTo CASP (Critical Assessment of protein Structure Prediction)
Protein Data Bank
releaseDate 2018
repository GitHub
sponsor Alphabet Inc.
supports proteins from many organisms
task protein structure prediction
usedBy academic researchers
pharmaceutical companies
usedFor drug discovery
functional annotation of proteins
protein engineering
uses deep learning
neural networks

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Referenced by (31)

Full triples — surface form annotated when it differs from this entity's canonical label.

DeepMind knownFor AlphaFold
DeepMind developed AlphaFold
Demis Hassabis knownFor AlphaFold
AlphaFold majorUpdate AlphaFold2
linked to: AlphaFold
Demis Hassabis knownFor AlphaFold
subject linked to: Demis
Jumper et al., Nature 2021 describes AlphaFold2
linked to: AlphaFold
John Jumper notableWork AlphaFold
John Jumper notablePublication Highly accurate protein structure prediction with AlphaFold
linked to: AlphaFold
Richard Evans contributedTo AlphaFold protein structure prediction system
linked to: AlphaFold
Richard Evans coauthorWith AlphaFold research team
linked to: AlphaFold
Richard Evans notableWork AlphaFold 2021 Nature paper
linked to: AlphaFold
Richard Evans partOf AlphaFold project at DeepMind
linked to: AlphaFold
Tim Green notableWork AlphaFold
Kathryn Tunyasuvunakool notableWork AlphaFold protein structure prediction system
linked to: AlphaFold
Augustin Žídek notableWork AlphaFold protein structure prediction system
linked to: AlphaFold
Augustin Žídek hasGivenTalkOn AlphaFold
Bernhard Romera-Paredes contributedTo AlphaFold protein structure prediction system
linked to: AlphaFold
2021 Nature AlphaFold paper mainSubject AlphaFold
subject linked to: Stanislav Nikolov
2021 Nature paper on AlphaFold protein structure prediction system mainSubject AlphaFold protein structure prediction system
subject linked to: Rishub Jain
linked to: AlphaFold
Trevor Back contributedTo AlphaFold
Michal Zielinski contributedTo AlphaFold
Highly accurate protein structure prediction with AlphaFold mainSubject AlphaFold
subject linked to: Michal Zielinski
Mona Pacholska coAuthorOf 2021 Nature paper "Highly accurate protein structure prediction with AlphaFold"
linked to: AlphaFold
Mona Pacholska associatedWith AlphaFold project
linked to: AlphaFold
Andrew W. Senior notableWork AlphaFold
Stig Petersen associatedWith AlphaFold project
linked to: AlphaFold
2021 Nature paper on AlphaFold protein structure prediction describes AlphaFold protein structure prediction system
subject linked to: David Reiman
linked to: AlphaFold
Clemens Meyer notableWork AlphaFold protein structure prediction system
linked to: AlphaFold