E1cB elimination

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf chemical reaction mechanism
gptkbp:contrastsWith gptkb:E2_elimination
gptkb:E1_elimination
gptkbp:example dehydrohalogenation of halo ketones
elimination of HCN from cyanohydrins
gptkbp:firstDescribed mid-20th century
gptkbp:fullName Elimination Unimolecular conjugate Base
https://www.w3.org/2000/01/rdf-schema#label E1cB elimination
gptkbp:mechanismOfAction gptkb:two-step
gptkbp:medium carbanion
gptkbp:namedFor E1cB stands for Elimination, Unimolecular, conjugate Base
gptkbp:numberOfStages deprotonation to form carbanion
gptkbp:product alkene
gptkbp:rateDeterminingStep loss of leaving group
gptkbp:requires strong base
gptkbp:stable electron-withdrawing groups
gptkbp:step loss of leaving group
gptkbp:studiedIn organic chemistry
gptkbp:substrate compounds with electron-withdrawing groups
compounds with poor leaving groups
gptkbp:type elimination reaction
gptkbp:bfsParent gptkb:E2_elimination
gptkbp:bfsLayer 7