Mediator complex
E1552444
UNEXPLORED
The Mediator complex is a large, multi-protein transcriptional coactivator that bridges gene-specific regulatory factors and RNA polymerase II to control eukaryotic gene expression.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Mediator complex canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T22693409 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Mediator complex Context triple: [RNA polymerase II, interactsWith, Mediator complex]
-
A.
TATA-binding protein associated factors
TATA-binding protein associated factors (TAFs) are a group of proteins that form part of the TFIID complex, playing a central role in recognizing promoter DNA and regulating transcription initiation by RNA polymerase II.
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B.
TFIID
TFIID is a multi-subunit transcription factor complex that recognizes core promoter elements and helps recruit RNA polymerase II to initiate gene transcription in eukaryotic cells.
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C.
Assembly of the Union complex
Assembly of the Union complex is the main parliamentary building complex of Myanmar, housing the national legislature in the capital Naypyidaw.
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D.
SMCR8-WDR41 complex
The SMCR8-WDR41 complex is a protein assembly that partners with C9orf72 to regulate autophagy and lysosomal function, particularly in the context of neurodegenerative disease mechanisms.
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E.
RNA polymerase II
RNA polymerase II is the eukaryotic enzyme complex responsible for transcribing DNA into messenger RNA and many non-coding RNAs, playing a central role in gene expression.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Mediator complex Target entity description: The Mediator complex is a large, multi-protein transcriptional coactivator that bridges gene-specific regulatory factors and RNA polymerase II to control eukaryotic gene expression.
-
A.
TATA-binding protein associated factors
TATA-binding protein associated factors (TAFs) are a group of proteins that form part of the TFIID complex, playing a central role in recognizing promoter DNA and regulating transcription initiation by RNA polymerase II.
-
B.
TFIID
TFIID is a multi-subunit transcription factor complex that recognizes core promoter elements and helps recruit RNA polymerase II to initiate gene transcription in eukaryotic cells.
-
C.
Assembly of the Union complex
Assembly of the Union complex is the main parliamentary building complex of Myanmar, housing the national legislature in the capital Naypyidaw.
-
D.
SMCR8-WDR41 complex
The SMCR8-WDR41 complex is a protein assembly that partners with C9orf72 to regulate autophagy and lysosomal function, particularly in the context of neurodegenerative disease mechanisms.
-
E.
RNA polymerase II
RNA polymerase II is the eukaryotic enzyme complex responsible for transcribing DNA into messenger RNA and many non-coding RNAs, playing a central role in gene expression.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.