DDIT3
E1551061
UNEXPLORED
DDIT3, also known as CHOP, is a stress-inducible transcription factor involved in endoplasmic reticulum stress responses and apoptosis, and is implicated in certain cancers through gene fusions.
All labels observed (1)
| Label | Occurrences |
|---|---|
| DDIT3 canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T22693521 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: DDIT3 Context triple: [EWSR1, formsFusionWith, DDIT3]
-
A.
Cln3
Cln3 is a G1 cyclin in budding yeast that helps trigger the Start transition of the cell cycle by activating the Cdc28 cyclin-dependent kinase.
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B.
IDH
IDH is the standard abbreviation used for the Idaho Steelheads professional ice hockey team.
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C.
GRIN3A
GRIN3A is a gene that encodes a subunit of the N-methyl-D-aspartate (NMDA) receptor, a key glutamate-gated ion channel involved in synaptic transmission and plasticity in the central nervous system.
-
D.
TARDBP
TARDBP is a gene encoding the TDP-43 protein, a DNA/RNA-binding protein whose abnormal aggregation is a key pathological feature in amyotrophic lateral sclerosis and related neurodegenerative diseases.
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E.
GRIN3B
GRIN3B is a human gene that encodes the GluN3B subunit of NMDA-type glutamate receptors involved in excitatory neurotransmission and synaptic plasticity in the central nervous system.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: DDIT3 Target entity description: DDIT3, also known as CHOP, is a stress-inducible transcription factor involved in endoplasmic reticulum stress responses and apoptosis, and is implicated in certain cancers through gene fusions.
-
A.
Cln3
Cln3 is a G1 cyclin in budding yeast that helps trigger the Start transition of the cell cycle by activating the Cdc28 cyclin-dependent kinase.
-
B.
IDH
IDH is the standard abbreviation used for the Idaho Steelheads professional ice hockey team.
-
C.
GRIN3A
GRIN3A is a gene that encodes a subunit of the N-methyl-D-aspartate (NMDA) receptor, a key glutamate-gated ion channel involved in synaptic transmission and plasticity in the central nervous system.
-
D.
TARDBP
TARDBP is a gene encoding the TDP-43 protein, a DNA/RNA-binding protein whose abnormal aggregation is a key pathological feature in amyotrophic lateral sclerosis and related neurodegenerative diseases.
-
E.
GRIN3B
GRIN3B is a human gene that encodes the GluN3B subunit of NMDA-type glutamate receptors involved in excitatory neurotransmission and synaptic plasticity in the central nervous system.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.