TFIIB
E1551043
UNEXPLORED
TFIIB is a general transcription factor that helps recruit and position RNA polymerase II at gene promoters to initiate transcription in eukaryotic cells.
All labels observed (1)
| Label | Occurrences |
|---|---|
| TFIIB canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T22693405 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: TFIIB Context triple: [RNA polymerase II, interactsWith, TFIIB]
-
A.
CTCF
CTCF is a state prison facility in Colorado that houses incarcerated individuals under the jurisdiction of the Colorado Department of Corrections.
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B.
RNA polymerase II
RNA polymerase II is the eukaryotic enzyme complex responsible for transcribing DNA into messenger RNA and many non-coding RNAs, playing a central role in gene expression.
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C.
MAFA transcription factor
MAFA transcription factor is a beta cell–specific transcription factor that plays a key role in regulating insulin gene expression and pancreatic islet function.
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D.
FOXA2 transcription factor
FOXA2 transcription factor is a forkhead box transcription factor that plays a key role in regulating genes involved in pancreatic beta-cell function, glucose metabolism, and endoderm development.
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E.
TARDBP
TARDBP is a gene encoding the TDP-43 protein, a DNA/RNA-binding protein whose abnormal aggregation is a key pathological feature in amyotrophic lateral sclerosis and related neurodegenerative diseases.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: TFIIB Target entity description: TFIIB is a general transcription factor that helps recruit and position RNA polymerase II at gene promoters to initiate transcription in eukaryotic cells.
-
A.
CTCF
CTCF is a state prison facility in Colorado that houses incarcerated individuals under the jurisdiction of the Colorado Department of Corrections.
-
B.
RNA polymerase II
RNA polymerase II is the eukaryotic enzyme complex responsible for transcribing DNA into messenger RNA and many non-coding RNAs, playing a central role in gene expression.
-
C.
MAFA transcription factor
MAFA transcription factor is a beta cell–specific transcription factor that plays a key role in regulating insulin gene expression and pancreatic islet function.
-
D.
fibrillarin
Fibrillarin is a highly conserved nucleolar protein that functions as a core component of small nucleolar ribonucleoproteins (snoRNPs), playing a key role in rRNA processing and ribosome biogenesis.
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E.
FOXA2 transcription factor
FOXA2 transcription factor is a forkhead box transcription factor that plays a key role in regulating genes involved in pancreatic beta-cell function, glucose metabolism, and endoderm development.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.