CDK7 kinase
E1551041
UNEXPLORED
CDK7 kinase is a cyclin-dependent kinase that functions as a key regulator of transcription initiation and cell cycle control by phosphorylating the C-terminal domain of RNA polymerase II and activating other CDKs.
All labels observed (1)
| Label | Occurrences |
|---|---|
| CDK7 kinase canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T22693389 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: CDK7 kinase Context triple: [RNA polymerase II, isRegulatedBy, CDK7 kinase]
-
A.
CDK6
CDK6 is a cyclin-dependent kinase that regulates cell cycle progression and is a key target in certain cancer therapies.
-
B.
Cdc28
Cdc28 is the major cyclin-dependent kinase in budding yeast that drives progression through the cell cycle by phosphorylating key regulatory proteins.
-
C.
CDK4
CDK4 is a cyclin-dependent kinase that regulates cell cycle progression and is a key therapeutic target in certain cancers.
-
D.
cyclin D2
Cyclin D2 is a regulatory protein that controls progression through the G1 phase of the cell cycle by activating cyclin-dependent kinases involved in cell proliferation.
-
E.
Cdh1
Cdh1 is a regulatory protein that activates the anaphase-promoting complex/cyclosome (APC/C) to control mitotic exit and G1 phase progression in the cell cycle.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: CDK7 kinase Target entity description: CDK7 kinase is a cyclin-dependent kinase that functions as a key regulator of transcription initiation and cell cycle control by phosphorylating the C-terminal domain of RNA polymerase II and activating other CDKs.
-
A.
CDK6
CDK6 is a cyclin-dependent kinase that regulates cell cycle progression and is a key target in certain cancer therapies.
-
B.
Cdc28
Cdc28 is the major cyclin-dependent kinase in budding yeast that drives progression through the cell cycle by phosphorylating key regulatory proteins.
-
C.
CDK4
CDK4 is a cyclin-dependent kinase that regulates cell cycle progression and is a key therapeutic target in certain cancers.
-
D.
cyclin D2
Cyclin D2 is a regulatory protein that controls progression through the G1 phase of the cell cycle by activating cyclin-dependent kinases involved in cell proliferation.
-
E.
Cdh1
Cdh1 is a regulatory protein that activates the anaphase-promoting complex/cyclosome (APC/C) to control mitotic exit and G1 phase progression in the cell cycle.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.