IL-17RA
E1549325
UNEXPLORED
IL-17RA is a cell surface receptor subunit that mediates signaling for interleukin-17 family cytokines, playing a key role in inflammatory and autoimmune responses.
All labels observed (2)
| Label | Occurrences |
|---|---|
| IL-17 receptor complex | 1 |
| IL-17RA canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T22690345 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: IL-17RA Context triple: [IL-17A, receptor, IL-17RA]
-
A.
IL-17A
IL-17A is a pro-inflammatory cytokine produced mainly by Th17 cells that plays a key role in the pathogenesis of several autoimmune and inflammatory diseases.
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B.
IL-64
IL-64 is a major east–west state highway in Illinois that runs from the Mississippi River through the Chicago metropolitan area.
-
C.
Janus kinase 1
Janus kinase 1 is a tyrosine kinase enzyme involved in cytokine receptor signaling and immune regulation, making it an important therapeutic target in inflammatory and autoimmune diseases.
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D.
IL18
IL18 is the ICAO aircraft type designator for the Soviet-era Ilyushin Il-18 long-range turboprop airliner.
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E.
interleukin-4
Interleukin-4 is an immune signaling cytokine that promotes B cell proliferation, differentiation, and antibody class switching, particularly toward IgE production.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: IL-17RA Target entity description: IL-17RA is a cell surface receptor subunit that mediates signaling for interleukin-17 family cytokines, playing a key role in inflammatory and autoimmune responses.
-
A.
IL-17A
IL-17A is a pro-inflammatory cytokine produced mainly by Th17 cells that plays a key role in the pathogenesis of several autoimmune and inflammatory diseases.
-
B.
IL-64
IL-64 is a major east–west state highway in Illinois that runs from the Mississippi River through the Chicago metropolitan area.
-
C.
Janus kinase 1
Janus kinase 1 is a tyrosine kinase enzyme involved in cytokine receptor signaling and immune regulation, making it an important therapeutic target in inflammatory and autoimmune diseases.
-
D.
IL18
IL18 is the ICAO aircraft type designator for the Soviet-era Ilyushin Il-18 long-range turboprop airliner.
-
E.
interleukin-4
Interleukin-4 is an immune signaling cytokine that promotes B cell proliferation, differentiation, and antibody class switching, particularly toward IgE production.
- F. None of above. chosen
Referenced by (2)
Full triples — surface form annotated when it differs from this entity's canonical label.