Cln3
E1539813
UNEXPLORED
Cln3 is a G1 cyclin in budding yeast that helps trigger the Start transition of the cell cycle by activating the Cdc28 cyclin-dependent kinase.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Cln3 canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T22516252 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Cln3 Context triple: [Cdc28, formsComplexWith, Cln3]
-
A.
SOD1
SOD1 is a gene encoding the antioxidant enzyme superoxide dismutase 1, whose mutations are a major known cause of familial amyotrophic lateral sclerosis (ALS).
-
B.
C9orf72
C9orf72 is a human gene whose hexanucleotide repeat expansions are the most common known genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
-
C.
GRIN3A
GRIN3A is a gene that encodes a subunit of the N-methyl-D-aspartate (NMDA) receptor, a key glutamate-gated ion channel involved in synaptic transmission and plasticity in the central nervous system.
-
D.
GRIN3B
GRIN3B is a human gene that encodes the GluN3B subunit of NMDA-type glutamate receptors involved in excitatory neurotransmission and synaptic plasticity in the central nervous system.
-
E.
SMN complex
The SMN complex is a multiprotein assembly crucial for the biogenesis of small nuclear ribonucleoproteins (snRNPs) and proper pre-mRNA splicing, with key roles in motor neuron survival.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Cln3 Target entity description: Cln3 is a G1 cyclin in budding yeast that helps trigger the Start transition of the cell cycle by activating the Cdc28 cyclin-dependent kinase.
-
A.
SOD1
SOD1 is a gene encoding the antioxidant enzyme superoxide dismutase 1, whose mutations are a major known cause of familial amyotrophic lateral sclerosis (ALS).
-
B.
C9orf72
C9orf72 is a human gene whose hexanucleotide repeat expansions are the most common known genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
-
C.
GRIN3A
GRIN3A is a gene that encodes a subunit of the N-methyl-D-aspartate (NMDA) receptor, a key glutamate-gated ion channel involved in synaptic transmission and plasticity in the central nervous system.
-
D.
GRIN3B
GRIN3B is a human gene that encodes the GluN3B subunit of NMDA-type glutamate receptors involved in excitatory neurotransmission and synaptic plasticity in the central nervous system.
-
E.
SMN complex
The SMN complex is a multiprotein assembly crucial for the biogenesis of small nuclear ribonucleoproteins (snRNPs) and proper pre-mRNA splicing, with key roles in motor neuron survival.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.