GRIN2A
E1407317
UNEXPLORED
GRIN2A is a gene that encodes the GluN2A subunit of NMDA-type glutamate receptors, which are critical for synaptic plasticity, learning, and memory in the brain.
All labels observed (1)
| Label | Occurrences |
|---|---|
| GRIN2A canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T19992809 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: GRIN2A Context triple: [NMDA receptor, encodedBy, GRIN2A]
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A.
GRIN1
GRIN1 is a gene that encodes an essential subunit of NMDA-type glutamate receptors, which play a key role in synaptic transmission and plasticity in the central nervous system.
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B.
SCN1A
SCN1A is a human gene encoding a neuronal voltage-gated sodium channel alpha subunit whose mutations are a major cause of Dravet syndrome and other epilepsy disorders.
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C.
GRIN2D
GRIN2D is a gene that encodes the GluN2D subunit of NMDA-type glutamate receptors, which are critical for synaptic transmission and plasticity in the central nervous system.
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D.
GNAS
GNAS is the abbreviation for the Georgian National Academy of Sciences, the leading scientific institution in Georgia that coordinates and promotes research across various disciplines.
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E.
HTT gene
The HTT gene encodes the huntingtin protein, and mutations in this gene—particularly CAG trinucleotide repeat expansions—cause Huntington's disease, a progressive neurodegenerative disorder.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: GRIN2A Target entity description: GRIN2A is a gene that encodes the GluN2A subunit of NMDA-type glutamate receptors, which are critical for synaptic plasticity, learning, and memory in the brain.
-
A.
GRIN1
GRIN1 is a gene that encodes an essential subunit of NMDA-type glutamate receptors, which play a key role in synaptic transmission and plasticity in the central nervous system.
-
B.
SCN1A
SCN1A is a human gene encoding a neuronal voltage-gated sodium channel alpha subunit whose mutations are a major cause of Dravet syndrome and other epilepsy disorders.
-
C.
GRIN2D
GRIN2D is a gene that encodes the GluN2D subunit of NMDA-type glutamate receptors, which are critical for synaptic transmission and plasticity in the central nervous system.
-
D.
GNAS
GNAS is the abbreviation for the Georgian National Academy of Sciences, the leading scientific institution in Georgia that coordinates and promotes research across various disciplines.
-
E.
HTT gene
The HTT gene encodes the huntingtin protein, and mutations in this gene—particularly CAG trinucleotide repeat expansions—cause Huntington's disease, a progressive neurodegenerative disorder.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.