GluN2A
E1407316
UNEXPLORED
GluN2A is a subunit of NMDA-type glutamate receptors that plays a key role in synaptic transmission and plasticity in the central nervous system.
All labels observed (1)
| Label | Occurrences |
|---|---|
| GluN2A canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T19992802 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: GluN2A Context triple: [NMDA receptor, hasSubunit, GluN2A]
-
A.
NMDA receptor
The NMDA receptor is a glutamate-activated ion channel in the brain that plays a key role in synaptic plasticity, learning, and memory, and is implicated in various neurological and psychiatric disorders.
-
B.
AMPA receptors
AMPA receptors are fast-acting ionotropic glutamate receptors in the brain that mediate most rapid excitatory synaptic transmission and play key roles in synaptic plasticity and learning.
-
C.
GABA-A receptor
The GABA-A receptor is a ligand-gated chloride ion channel in the central nervous system that mediates fast inhibitory neurotransmission and is a primary target of many sedative, anxiolytic, and hypnotic drugs.
-
D.
GRIN1
GRIN1 is a gene that encodes an essential subunit of NMDA-type glutamate receptors, which play a key role in synaptic transmission and plasticity in the central nervous system.
-
E.
CaMKII
CaMKII (Calcium/calmodulin-dependent protein kinase II) is a key serine/threonine kinase in neurons that decodes calcium signals to regulate synaptic plasticity, learning, and memory.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: GluN2A Target entity description: GluN2A is a subunit of NMDA-type glutamate receptors that plays a key role in synaptic transmission and plasticity in the central nervous system.
-
A.
NMDA receptor
The NMDA receptor is a glutamate-activated ion channel in the brain that plays a key role in synaptic plasticity, learning, and memory, and is implicated in various neurological and psychiatric disorders.
-
B.
AMPA receptors
AMPA receptors are fast-acting ionotropic glutamate receptors in the brain that mediate most rapid excitatory synaptic transmission and play key roles in synaptic plasticity and learning.
-
C.
GABA-A receptor
The GABA-A receptor is a ligand-gated chloride ion channel in the central nervous system that mediates fast inhibitory neurotransmission and is a primary target of many sedative, anxiolytic, and hypnotic drugs.
-
D.
GRIN1
GRIN1 is a gene that encodes an essential subunit of NMDA-type glutamate receptors, which play a key role in synaptic transmission and plasticity in the central nervous system.
-
E.
CaMKII
CaMKII (Calcium/calmodulin-dependent protein kinase II) is a key serine/threonine kinase in neurons that decodes calcium signals to regulate synaptic plasticity, learning, and memory.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.