Statements (33)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:drug
antiarrhythmic agent |
gptkbp:approvalYear |
1999 (US)
|
gptkbp:ATCCode |
C01BD04
|
gptkbp:brand |
Tikosyn
|
gptkbp:CASNumber |
115256-11-6
|
gptkbp:contraindication |
gptkb:congenital_long_QT_syndrome
severe renal impairment concurrent use with verapamil |
gptkbp:developer |
gptkb:Pfizer
|
gptkbp:eliminationHalfLife |
10 hours
|
gptkbp:excretion |
urine
|
gptkbp:hasMolecularFormula |
C19H27N3O5S2
|
https://www.w3.org/2000/01/rdf-schema#label |
Dofetilide
|
gptkbp:KEGGID |
D07713
|
gptkbp:legalStatus |
prescription only
|
gptkbp:mechanismOfAction |
potassium channel blocker
class III antiarrhythmic |
gptkbp:metabolism |
liver
|
gptkbp:pregnancyCategory |
C (US)
|
gptkbp:PubChem_CID |
3152
CHEMBL1201312 DB00204 |
gptkbp:routeOfAdministration |
oral
|
gptkbp:sideEffect |
gptkb:torsades_de_pointes
dizziness headache ventricular arrhythmia |
gptkbp:UNII |
8L70Q75FXE
|
gptkbp:usedFor |
gptkb:atrial_fibrillation
atrial flutter |
gptkbp:bfsParent |
gptkb:Atrial_Flutter
|
gptkbp:bfsLayer |
7
|