Dofetilide

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:drug
antiarrhythmic agent
gptkbp:approvalYear 1999 (US)
gptkbp:ATCCode C01BD04
gptkbp:brand Tikosyn
gptkbp:CASNumber 115256-11-6
gptkbp:contraindication gptkb:congenital_long_QT_syndrome
severe renal impairment
concurrent use with verapamil
gptkbp:developer gptkb:Pfizer
gptkbp:eliminationHalfLife 10 hours
gptkbp:excretion urine
gptkbp:hasMolecularFormula C19H27N3O5S2
https://www.w3.org/2000/01/rdf-schema#label Dofetilide
gptkbp:KEGGID D07713
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction potassium channel blocker
class III antiarrhythmic
gptkbp:metabolism liver
gptkbp:pregnancyCategory C (US)
gptkbp:PubChem_CID 3152
CHEMBL1201312
DB00204
gptkbp:routeOfAdministration oral
gptkbp:sideEffect gptkb:torsades_de_pointes
dizziness
headache
ventricular arrhythmia
gptkbp:UNII 8L70Q75FXE
gptkbp:usedFor gptkb:atrial_fibrillation
atrial flutter
gptkbp:bfsParent gptkb:Atrial_Flutter
gptkbp:bfsLayer 7