|
gptkbp:instance_of
|
gptkb:pharmaceuticals
|
|
gptkbp:administered_by
|
oral capsule
|
|
gptkbp:approves
|
gptkb:2020
gptkb:FDA
|
|
gptkbp:brand
|
gptkb:Vumerity
|
|
gptkbp:casnumber
|
1202560-51-8
|
|
gptkbp:chemical_formula
|
C12 H14 N2 O4
|
|
gptkbp:class
|
disease-modifying therapy
fumarate ester
|
|
gptkbp:clinical_trial
|
Phase 3 trials
Phase 2 and 3
|
|
gptkbp:clinical_use
|
chronic treatment
|
|
gptkbp:contraindication
|
hypersensitivity to the drug
|
|
gptkbp:developed_by
|
gptkb:Biogen
|
|
gptkbp:dosage_form
|
gptkb:capsule
twice daily
|
|
gptkbp:duration
|
long-term therapy
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:financial_support
|
available for patients
monitor liver function
|
|
gptkbp:formulation
|
delayed-release
|
|
gptkbp:healthcare
|
prescribed by neurologists
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Diroximel Fumarate
|
|
gptkbp:indication
|
gptkb:relapsing_forms_of_multiple_sclerosis
|
|
gptkbp:ingredients
|
gptkb:Diroximel_Fumarate
|
|
gptkbp:interacts_with
|
may interact with immunosuppressants
|
|
gptkbp:is_effective_against
|
reduces relapse rates
|
|
gptkbp:lifespan
|
approximately 1 hour
|
|
gptkbp:market_launch
|
gptkb:2020
|
|
gptkbp:marketed_as
|
gptkb:Vumerity
|
|
gptkbp:mechanism_of_action
|
anti-inflammatory
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:packaging
|
bottles of 30 capsules
|
|
gptkbp:patient_education
|
important for adherence
|
|
gptkbp:patient_population
|
adults
|
|
gptkbp:pharmacokinetics
|
modulates immune response
absorbed in gastrointestinal tract
|
|
gptkbp:provides_guidance_on
|
MS treatment guidelines
|
|
gptkbp:regulatory_compliance
|
FDA approved
|
|
gptkbp:related_to
|
gptkb:Dimethyl_Fumarate
|
|
gptkbp:research
|
ongoing studies on efficacy
|
|
gptkbp:research_focus
|
neurological disorders
|
|
gptkbp:route_of_administration
|
oral
|
|
gptkbp:safety_features
|
generally well tolerated
|
|
gptkbp:side_effect
|
headache
nausea
abdominal pain
diarrhea
flushing
elevated liver enzymes
|
|
gptkbp:storage
|
store at room temperature
|
|
gptkbp:supply_chain
|
manufactured by Biogen
|
|
gptkbp:treatment
|
improved quality of life
reduce disease activity
|
|
gptkbp:used_for
|
treatment of multiple sclerosis
|
|
gptkbp:bfsParent
|
gptkb:Biogen_Idec
|
|
gptkbp:bfsLayer
|
5
|