Diabetic Nephropathy

GPTKB entity

Statements (49)
Predicate Object
gptkbp:instanceOf gptkb:disease
complication of diabetes
gptkbp:affects kidneys
gptkbp:alsoKnownAs diabetic kidney disease
gptkbp:associatedWith gptkb:cardiovascular_disease
peripheral neuropathy
retinopathy
gptkbp:cause renal failure
chronic kidney disease
end-stage renal disease
nephrotic syndrome
gptkbp:causedBy gptkb:diabetes_mellitus_type_2
diabetes mellitus type 1
gptkbp:complication gptkb:diabetes_mellitus
gptkbp:diagnosedBy urine albumin test
glomerular filtration rate measurement
gptkbp:firstDescribed 1936
gptkbp:hasEpidemiology leading cause of kidney failure worldwide
gptkbp:histology basement membrane thickening
glomerulosclerosis
mesangial expansion
https://www.w3.org/2000/01/rdf-schema#label Diabetic Nephropathy
gptkbp:ICD-10_code E10.2
E11.2
gptkbp:MeSH_ID gptkb:D003928
gptkbp:mortalityRisk increased
gptkbp:numberOfStages end-stage renal disease
renal insufficiency
macroalbuminuria
microalbuminuria
gptkbp:prevalence common in long-standing diabetes
gptkbp:prevention lifestyle modification
blood pressure management
tight blood sugar control
gptkbp:progression can be slowed with treatment
gptkbp:riskFactor smoking
hypertension
genetic predisposition
poor glycemic control
gptkbp:symptom edema
hypertension
proteinuria
gptkbp:treatment ACE inhibitors
blood pressure control
glycemic control
angiotensin II receptor blockers
dietary protein restriction
gptkbp:bfsParent gptkb:DKD
gptkbp:bfsLayer 7