Diabetes Mellitus, Insulin-Resistant

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:disease
gptkbp:affects	adults children (increasingly)
gptkbp:alsoKnownAs	gptkb:Type_2_Diabetes_Mellitus
gptkbp:associatedWith	gptkb:polycystic_ovary_syndrome gptkb:metabolic_syndrome gptkb:nonalcoholic_fatty_liver_disease
gptkbp:cause	macrovascular complications microvascular complications
gptkbp:characterizedBy	insulin resistance hyperglycemia
gptkbp:complication	gptkb:peripheral_neuropathy gptkb:cardiovascular_disease gptkb:nephropathy retinopathy foot ulcers
gptkbp:diagnosedBy	gptkb:oral_glucose_tolerance_test HbA1c test fasting plasma glucose
gptkbp:firstDescribed	20th century
gptkbp:ICD-10_code	E11
gptkbp:managedBy	gptkb:exercise gptkb:food weight loss
gptkbp:prevalence	high worldwide increasing incidence
gptkbp:prevention	healthy diet weight control healthy lifestyle regular physical activity
gptkbp:riskFactor	obesity hypertension sedentary lifestyle older age dyslipidemia family history of diabetes
gptkbp:symptom	fatigue blurred vision polydipsia polyuria
gptkbp:treatment	gptkb:metformin gptkb:GLP-1_receptor_agonists gptkb:SGLT2_inhibitors lifestyle modification sulfonylureas insulin (in advanced cases)
gptkbp:bfsParent	gptkb:D004053
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	Diabetes Mellitus, Insulin-Resistant